2226-96-2

  • Product Name4-HYDROXY-2,2,6,6-TETRAMETHYLPIPERIDINYLOXY
  • Molecular FormulaC9H18NO2
  • Molecular Weight174.263
  • Purity99%
  • Appearanceorange crystals
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Product Details

Quick Details

  • CasNo: 2226-96-2
  • Molecular Formula: C9H18NO2
  • Appearance: orange crystals
  • Purity: 99%

Chemical plants supply high-quality 4-HYDROXY-2,2,6,6-TETRAMETHYLPIPERIDINYLOXY 2226-96-2 in bulk

  • Molecular Formula:C9H18NO2
  • Molecular Weight:174.263
  • Appearance/Colour:orange crystals 
  • Vapor Pressure:0.025Pa at 20℃ 
  • Melting Point:69-71 °C(lit.) 
  • Refractive Index:1.4350 (estimate) 
  • Boiling Point:269ºC 
  • PKA:5.07[at 20 ℃] 
  • Flash Point:146°(295°F) 
  • PSA:23.47000 
  • Density:1.187 g/cm3 
  • LogP:1.28370 

4-Hydroxy-2,2,6,6-tetramethyl-piperidinooxy(Cas 2226-96-2) Usage

Synthesis Reference(s)

Synthetic Communications, 19, p. 3509, 1989 DOI: 10.1080/00397918908052760

Flammability and Explosibility

Nonflammable

Biological Activity

Superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects.

General Description

4-Hydroxy-TEMPO is a 4-substituted 2,2,6,6-tetramethylpiperidyl-1-oxy (TEMPO) derivative. It is a low-molecular weight compound and has been proposed as superoxide dismutase mimic.

InChI:InChI=1/C9H18NO2/c1-8(2)5-7(11)6-9(3,4)10(8)12/h7,11H,5-6H2,1-4H3

2226-96-2 Relevant articles

Photoinduced oxidation of sterically hindered amines in acetonitrile solutions and titania suspensions (An EPR Study)

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The reactions of sterically hindered ami...

EPR Study of Membrane Partitioning, Orientation, and Membrane-Modulated Alkaline Hydrolysis of a Spin-Labeled Benzoic Acid Ester

Bianconi, M. Lucia,Schreier, Shirley

, p. 2483 - 2486 (1991)

The composite EPR spectra of a spin prob...

Reactions of nitroxides. Part XII [1]. - 2,2,6,6-tetramethyl-l-oxyl-4- piperidyl chloroformate - A new reactive nitroxyl radical. a one-pot synthesis of 2,2,6,6-tetramethyl-1-oxyl-4-piperidyl N,N-dialkyl-carbamates

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The reactive nitroxides 2,2,6,6-tetramet...

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Chemotherapy is a general treatment opti...

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Weiner

, p. 526,527 (1969)

-

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Cunha, Anna C.,Ferreira, Vitor F.,Vaz, Maria G. F.,Cassaro, Rafael A. All?o,Resende, Jackson A. L. C.,Sacramento, Carolina Q.,Costa, Jéssica,Abrantes, Juliana L.,Souza, Thiago Moreno L.,Jord?o, Alessandro K.

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Ultrafast and reversible multiblock formation by the SET-nitroxide radical coupling reaction

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, p. 1227 - 1236 (2010)

The single electron transfer-nitroxide r...

Kinetics of oxidation and comproportionation reactions involving an oxammonium ion, benzyl alcohol and methyltrioxorhenium(VII)

Zauche, Timothy H.,Espenson, James H.

, p. 381 - 385 (1999)

The reactions of 4-hydroxy-2,2,6,6-tetra...

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-

Paragraph 0042-0045; 0058-0059, (2021/09/26)

The method comprises the following steps...

A cyanine dye based supramolecular photosensitizer enabling visible-light-driven organic reaction in water

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We report the aggregation-induced photos...

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Ito, Tomohiro,Konno, Hiroyuki,Sato, Shingo,Sugawara, Koya

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In this study, 3-hydroxymethyl-2,2,5,5-t...

2226-96-2 Process route

4-hydroxy-2,2,6,6-tetramethylpiperidine
2403-88-5

4-hydroxy-2,2,6,6-tetramethylpiperidine

TEMPOL
45985-24-8,2226-96-2

TEMPOL

4-oxo-2,2,6,6-tetramethylpiperidin-oxyl
45985-26-0,2896-70-0

4-oxo-2,2,6,6-tetramethylpiperidin-oxyl

Conditions
Conditions Yield
With potassium superoxide; In water; acetonitrile; at 21.84 ℃; Inert atmosphere; Irradiation;
TEMPO-OL
60462-93-3

TEMPO-OL

TEMPOL
45985-24-8,2226-96-2

TEMPOL

cis-Octadecenoic acid
112-80-1,2027-47-6

cis-Octadecenoic acid

Conditions
Conditions Yield
With water; lipase; for 37h; Product distribution;

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