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FGFR and VEGFR inhibitors are provided, ...
The present application relates to indol...
The present invention is directed to pyr...
6-Methylpyridazin-3(2H)-on
6-methyl-3-bromopyridazine
Conditions | Yield |
---|---|
With
phosphorus(V) oxybromide;
at 70 ℃;
|
31% |
6-Methylpyridazin-3(2H)-on;
With
phosphorus(V) oxybromide;
at 90 ℃;
for 1.5h;
Inert atmosphere;
With
sodium hydrogencarbonate;
In
water;
Cooling with ice;
|
Trifluoromethanesulfonic acid 6-methylpyridazine-3-yl ester
6-methyl-3-bromopyridazine
Conditions | Yield |
---|---|
With
sodium hydroxide; hydrogen bromide;
In
acetic acid;
|
6-methyl-2H-pyridazin-3-one; hydrobromide
Trifluoromethanesulfonic acid 6-methylpyridazine-3-yl ester
6-Methylpyridazin-3(2H)-on
4-oxopentanoic acid ethyl ester
3-hydrazinyl-6-methylpyridazine
3-bromo-6-(bromomethyl)pyridazine
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